The Real GI Doc Show

In this episode, Dr. Gandolfo explores a lesser-known side effect of heavy marijuana use: Cannabinoid Hyperemesis Syndrome (CHS). Although marijuana use is becoming even more prevalent, awareness of this severe vomiting illness still remains low.

Dr. Gandolfo shares a compelling case study of a young patient suffering from CHS, detailing the symptoms, diagnosis, and treatment options available for this condition.

Topics covered in this episode:

• Understanding Cannabinoid Hyperemesis Syndrome and its link to cyclic vomiting syndrome.
• The phases of cyclic vomiting and how they relate to CHS.
• The physiological mechanisms behind CHS, including the role of CB receptors and THC.
• The impact of high THC concentrations in modern marijuana products.
• Complications associated with CHS, from dehydration to more serious issues.
• Strategies for managing CHS, including the importance of long-term cessation of marijuana use.
• The role of therapy and medication in treating underlying anxiety and depression linked to heavy cannabis use.

Referenced in today's episode:

AGA Clinical Practice Update on CHS (2024)

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